BergaCare SmartLipids: commercial lipophilic active concentrates for improved performance of dermal products

• Florence Olechowski,
• Rainer H. Müller and
• Sung Min Pyo

Beilstein J. Nanotechnol. 2019, 10, 2152–2162, doi:10.3762/bjnano.10.208

• Abstract SmartLipids are the latest generation of dermal lipid nanoparticles with solid particle matrix. Their characteristic properties resulting from the “chaotic” and disordered particle matrix structure are reviewed. These properties are high loading and firm inclusion of active agents, physical

• carrier, so as to not distinctly affect the properties of the formulation, e.g., skin feeling; physical stability, i.e., firm inclusion of active agents and remaining integrity of the carriers in the final formulation during shelf life; effective protection and stabilization of chemically labile active

• solid at body temperature. In 2014 a new generation of carriers was developed, called SmartLipids [5][6]. They combine all the existing advantages of the previous particles made from solid lipids/lipid blends and add new key features. These are distinctly increased loading capacity and firm inclusion of